Skin Brightening 4 n butyl resorcinol 4-n-Butyl Resorcinol 18979-61-8 CAS NO.18979-61-8

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4-n-Butyl Resorcinol is an antioxidant that is considered effective in influencing the formation of pigmentation, and therefore able to lighten the skin. It is a synthetic compound that is partially derived from natural lightening compounds found in scotch pine bark, and is considered a reliable whitening agent.
According to studies when directly compared to B-Arbutin, Phenylethyl Resorcinol was shown to be over one hundred times as effective at lightening hair, and when tested in vivo on skin that had not been exposed to light, 0.5% concentrations of Phenylethyl Resorcinol proved to be more effective than 1.0% kojic acid.

1. Before melanin synthesis, it interferes with the synthesis and glycosylation of tyrosinase to prevent the enzyme from being absorbed by melanosome.

2. During the synthesis of melanin, it can inhibit the activity of enzyme and act as a competitive inhibitor of tyrosinase and TRP1 enzyme, reducing the formation of by-product of melanin.
3. After the synthesis of melanin, it can improve the degradation of tyrosinase, inhibit the transfer of melanosome to keratinocytes, and has the effect of light peeling due to the effect of fatty acids. This function is enhanced by the presence of fatty acids and regulates the degradation of tyrosinase.